Targeting of lanthanide(III) chelates of DOTA-type glycoconjugates to the hepatic asyaloglycoprotein receptor: cell internalization and animal imaging studies

The characterization of a new class of hydrophilic liver-targeted agents for gamma-scintigraphy and MRI, consisting, respectively, of [153Sm]3+ or Gd3+ complexes of DOTA monoamide or bisamide linked glycoconjugates (DOTA = 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid), is reported. In vi...

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Bibliographic Details
Main Author: Prata, M. I. M. (author)
Other Authors: Santos, A. C. (author), Torres, S. (author), André, J. P. (author), Martins, J. A. (author), Neves, M. (author), García-Martín, M. L. (author), Rodrigues, T. B. (author), López-Larrubia, P. (author), Cerdán, S. (author), Geraldes, C. F. G. C. (author)
Format: article
Language:eng
Published: 2006
Online Access:http://hdl.handle.net/10316/8442
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/8442

Internet

http://hdl.handle.net/10316/8442

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