The interface between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and selectively degrades mRNAs carrying premature termination codons (PTCs). In addition, several studies have also implicated NMD in the regulation of steady-state levels of physiological mRNAs, and examples of natural NMD...

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Detalhes bibliográficos
Autor principal: Onofre, Cláudia (author)
Outros Autores: Menezes, Juliane (author), Duarte, Andreia (author), Peixeiro, Isabel (author), Barbosa, Cristina (author), Costa, Paulo (author), Romão, Luísa (author)
Formato: conferenceObject
Idioma:eng
Publicado em: 2025
Assuntos:
Genómica Funcional e Estrutural
Expressão Génica
Síntese Proteica
Nonsense-mediated mRNA Decay
Texto completo:http://hdl.handle.net/10400.18/4435
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4435

Texto Completo

http://hdl.handle.net/10400.18/4435

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