The interface between mRNA translation and nonsense-mediated decay in AUG-proximal nonsense-mutated transcripts

Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that recognizes and selectively degrades mRNAs carrying premature termination codons (PTCs). In addition, several studies have also implicated NMD in the regulation of steady-state levels of physiological mRNAs, and examples of natural NMD...

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Bibliographic Details
Main Author: Onofre, Cláudia (author)
Other Authors: Menezes, Juliane (author), Duarte, Andreia (author), Peixeiro, Isabel (author), Barbosa, Cristina (author), Costa, Paulo (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2025
Subjects:
Genómica Funcional e Estrutural
Expressão Génica
Síntese Proteica
Nonsense-mediated mRNA Decay
Online Access:http://hdl.handle.net/10400.18/4435
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/4435

Internet

http://hdl.handle.net/10400.18/4435

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