Alternative splicing of tumour-related Rac1b is regulated by upstream signalling pathways
The small GTPase Rac1 regulates signalling pathways controlling actin-dependent cell motility as well as gene transcription. An alternative splicing variant Rac1b is overexpressed in a subset of colorectal tumours and cooperates with mutant B-Raf to sustain tumour cell viability. The alternative spl...
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| Other Authors: | , |
| Format: | conferenceObject |
| Language: | eng |
| Published: |
2011
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| Subjects: | |
| Online Access: | http://hdl.handle.net/10400.18/338 |
| Country: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/338 |