The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease

Objective Compromised brain cholesterol turnover and altered regulation of brain cholesterol metabolism have been allied with some neurodegenerative diseases, including Huntington’s disease (HD). Following our previous studies in HD, in this study we aim to investigate in vitro in a neuroblastoma ce...

ver descrição completa

Detalhes bibliográficos
Autor principal: Nóbrega, Clévio (author)
Outros Autores: Conceição, André (author), Costa, Rafael G (author), Koppenol, Rebekah (author), Sequeira, Raquel L. (author), Nunes, Ricardo (author), Carmo-Silva, Sara (author), Marcelo, Adriana (author), Matos, Carlos A (author), Betuing, Sandrine (author), Caboche, Jocelyne (author), Cartier, Nathalie (author), Alves, Sandro (author)
Formato: article
Idioma:eng
Publicado em: 2020
Texto completo:http://hdl.handle.net/10400.1/13861
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/13861

Texto Completo

http://hdl.handle.net/10400.1/13861

Registos relacionados