Contribution to the molecular characterization of osteoarthritis and osteoporosis phenotypes associated with hereditary hemochromatosis

In this study, we aimed to investigate the molecular mechanisms responsible for development of osteoarthritis (OA) and osteoporosis (OP) phenotypes in hereditary hemochromatosis using the Hfe-KO mouse model. Results from the analysis of Hfe-KO mice articular cartilage showed that Hfe loss of functio...

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Detalhes bibliográficos
Autor principal: F. Simao, Marcio (author)
Formato: doctoralThesis
Idioma:eng
Publicado em: 2019
Assuntos:
Texto completo:http://hdl.handle.net/10400.1/10812
País:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/10812