Contribution to the molecular characterization of osteoarthritis and osteoporosis phenotypes associated with hereditary hemochromatosis

In this study, we aimed to investigate the molecular mechanisms responsible for development of osteoarthritis (OA) and osteoporosis (OP) phenotypes in hereditary hemochromatosis using the Hfe-KO mouse model. Results from the analysis of Hfe-KO mice articular cartilage showed that Hfe loss of functio...

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Bibliographic Details
Main Author: F. Simao, Marcio (author)
Format: doctoralThesis
Language:eng
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/10400.1/10812
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/10812