In vivo toxicometabolomics reveals multi-organ and urine metabolic changes in mice upon acute exposure to human-relevant doses of 3,4-methylenedioxypyrovalerone (MDPV)

3,4-Methylenedioxypyrovalerone (MDPV) is consumed worldwide, despite its potential to cause toxicity in several organs and even death. There is a recognized need to clarify the biological pathways through which MDPV elicits general and target-organ toxicity. In this work, a comprehensive untargeted...

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Detalhes bibliográficos
Autor principal: Araújo, Ana Margarida (author)
Outros Autores: Carvalho, Márcia (author), Costa, Vera Marisa (author), Duarte, José Alberto (author), Dinis-Oliveira, Ricardo Jorge (author), Bastos, Maria de Lourdes (author), Guedes de Pinho, Paula (author), Carvalho, Félix (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
MDPV
GC–MS
Toxicometabolomics
In vivo
Multi-organ toxicity
Urine
Texto completo:http://hdl.handle.net/10284/9979
País:Portugal
Oai:oai:bdigital.ufp.pt:10284/9979

Texto Completo

http://hdl.handle.net/10284/9979

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