Transcription factor hypoxia-inducible factor (HIF)-1alpha is relevant for necrosis of Mycobacterium avium-induced granulomas.
Mycobacterial infections are characterized by the formation of granulomas. Granulomas are well-organized aggregates of immune cells, namely infected macrophages. The granuloma's main function is to constrain and prevent dissemination of the mycobacteria while concentrating the immune response t...
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| Format: | article |
| Language: | por |
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2014
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| Online Access: | https://hdl.handle.net/10216/82216 |
| Country: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/82216 |