Substance P antagonist improves both obesity and asthma in a mouse model

Evidence suggests a causal relationship between obesity and asthma; however, the underlying mechanisms remain unknown. Substance P (SP), involved in neurogenic inflammation by acting through its receptor NK1-R, seems to participate in obese–asthma phenotype in mice. To evaluate the effect of a selec...

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Detalhes bibliográficos
Autor principal: Ramalho, R. (author)
Outros Autores: Almeida, Joana (author), Beltrão, M. (author), Pirraco, A. (author), Costa, R. (author), Sokhatska, O. (author), Guardão, L. (author), Palmares, C. (author), Guimarães, J. T. (author), Delgado, L. (author), Moreira, A. (author), Soares, R. (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
Animal model
Asthma
NK1-R antagonist
Obesity
Substance P
Treatment
Texto completo:http://hdl.handle.net/10400.22/18592
País:Portugal
Oai:oai:recipp.ipp.pt:10400.22/18592

Texto Completo

http://hdl.handle.net/10400.22/18592

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