Combining hyaluronic acid with chitosan enhances gene delivery

The low gene transfer efficiency of chitosan-DNA polyplexes is a consequence of their high stability and consequent slow DNA release. The incorporation of an anionic polymer is believed to loosen chitosan interactions with DNA and thus promote higher transfection efficiencies. In this work, several...

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Bibliographic Details
Main Author: Oliveira, Ana (author)
Other Authors: Bitoque, Diogo (author), Silva, Gabriela (author)
Format: article
Language:eng
Published: 2018
Subjects:
Transfection efficiency
In-vivo
Nanoparticles
Expression
Carriers
Therapy
Cells
Cd44
Online Access:http://hdl.handle.net/10400.1/12033
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/12033

Internet

http://hdl.handle.net/10400.1/12033

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