Catalytic One-Pot Diastereoselective Michael-Initiated Ring-Closure of Methyl Ketones with 3-Bromochromones: Synthesis of Cyclopropa[b]chromanones

A one-pot diastereoselective base-catalyzed Michael-initiated ring-closure (MIRC) of activated methyl ketones with 3-bromochromones to give cyclopropa[b]chromanones is described. Three asymmetric centres are generated in the new cyclopropa[b]chromanone skeleton. Stereochemistry studies based on NMR...

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Detalhes bibliográficos
Autor principal: Sousa, Joana L. C. (author)
Outros Autores: Talhi, Oualid (author), Mendes, Ricardo F. (author), Almeida Paz, Filipe A. (author), Bachari, Khaldoun (author), Silva, Artur M. S. (author)
Formato: article
Idioma:eng
Publicado em: 1000
Assuntos:
1,2,3-TRISUBSTITUTED CYCLOPROPANES
NATURAL-PRODUCTS
MIRC REACTIONS
DISCOVERY
ANALOGS
AGENTS
Texto completo:http://hdl.handle.net/10773/20116
País:Portugal
Oai:oai:ria.ua.pt:10773/20116

Texto Completo

http://hdl.handle.net/10773/20116

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