Comparative metabolism of tramadol and tapentadol: a toxicological perspective
Tramadol and tapentadol are centrally acting, synthetic opioid analgesics used in the treatment of moderate to severe pain. Main metabolic patterns for these drugs in humans are well characterized. Tramadol is mainly metabolized by cytochrome P450 CYP2D6 to O-desmethyltramadol (M1), its main active...
| Autor principal: | |
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| Outros Autores: | , , , , |
| Formato: | other |
| Idioma: | eng |
| Publicado em: |
2016
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| Texto completo: | https://hdl.handle.net/10216/90471 |
| País: | Portugal |
| Oai: | oai:repositorio-aberto.up.pt:10216/90471 |