Comparative metabolism of tramadol and tapentadol: a toxicological perspective

Tramadol and tapentadol are centrally acting, synthetic opioid analgesics used in the treatment of moderate to severe pain. Main metabolic patterns for these drugs in humans are well characterized. Tramadol is mainly metabolized by cytochrome P450 CYP2D6 to O-desmethyltramadol (M1), its main active...

Full description

Bibliographic Details
Main Author: Barbosa, J (author)
Other Authors: Faria, J (author), Queiros, O (author), Moreira, R (author), Felix Carvalho (author), Ricardo Jorge Dinis Oliveira (author)
Format: other
Language:eng
Published: 2016
Online Access:https://hdl.handle.net/10216/90471
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/90471

Internet

https://hdl.handle.net/10216/90471

Similar Items