Recombinant production and purification of the R248W mutant of human p53 in Escherichia coli
The p53 protein is a tumour suppressor that specifically binds to DNA sequences to control gene expression. By controlling DNA repair, cell cycle arrest, and apoptosis, p53 prevents the dissemination of mutations within the genome. In about 50% of human cancer cases this protein is mutated. The muta...
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| Outros Autores: | , |
| Formato: | conferenceObject |
| Idioma: | eng |
| Publicado em: |
2019
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| Assuntos: | |
| Texto completo: | http://hdl.handle.net/1822/60539 |
| País: | Portugal |
| Oai: | oai:repositorium.sdum.uminho.pt:1822/60539 |