Delivery of Antisense Oligonucleotides Mediated by a Hydrogel System: In Vitro and In Vivo Application in the Context of Spinal Cord Injur

Biomaterials-based hydrogels are attractive drug-eluting vehicles in the context of RNA therapeutics, such as those utilizing antisense oligonucleotide or RNA interference based drugs, as they can potentially reduce systemic toxicity and enhance in vivo efficacy by increasing in situ concentrations....

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Detalhes bibliográficos
Autor principal: Moreno, PMD (author)
Outros Autores: Rodrigues, T (author), Torrado, M (author), Amaral, IF (author), Pêgo, AP (author)
Formato: book
Idioma:eng
Publicado em: 2019
Assuntos:
Texto completo:https://hdl.handle.net/10216/126851
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/126851