Delivery of Antisense Oligonucleotides Mediated by a Hydrogel System: In Vitro and In Vivo Application in the Context of Spinal Cord Injur

Biomaterials-based hydrogels are attractive drug-eluting vehicles in the context of RNA therapeutics, such as those utilizing antisense oligonucleotide or RNA interference based drugs, as they can potentially reduce systemic toxicity and enhance in vivo efficacy by increasing in situ concentrations....

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Bibliographic Details
Main Author: Moreno, PMD (author)
Other Authors: Rodrigues, T (author), Torrado, M (author), Amaral, IF (author), Pêgo, AP (author)
Format: book
Language:eng
Published: 2019
Subjects:
Online Access:https://hdl.handle.net/10216/126851
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/126851