TLR3 essentially promotes protective class I–restricted memory CD8+ T-cell responses to Aspergillus fumigatus in hematopoietic transplanted patients

Aspergillus fumigatus is a model fungal pathogen and a common cause of severe infections and diseases. CD8+ T cells are present in the human and murine T-cell repertoire to the fungus. However, CD8+ T-cell function in infection and the molecular mechanisms that control their priming and differentiat...

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Bibliographic Details
Main Author: Carvalho, Agostinho (author)
Other Authors: De Luca, Antonella (author), Bozza, Silvia (author), Cunha, Cristina (author), D’Angelo, Carmen (author), Moretti, Silvia (author), Perruccio, Katia (author), Iannitti, Rossana G. (author), Fallarino, Francesca (author), Antonio Pierini (author), Latgé, Jean-Paul (author), Velardi, Andrea (author), Aversa, Franco (author), Romani, Luigina (author)
Format: article
Language:eng
Published: 2012
Subjects:
TLR3
Aspergillosis
CD8+ T cells
Single nucleotide polymorphism
Science & Technology
Online Access:http://hdl.handle.net/1822/32458
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/32458

Internet

http://hdl.handle.net/1822/32458

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