Physiological characterization of a pyrimidine auxotroph exposes link between uracil phosphoribosyltransferase regulation and riboflavin production in Ashbya gossypii

The blockage of the de novo pyrimidine biosynthetic pathway at the orotidine-5-phosphate decarboxylase level was previously demonstrated to affect riboflavin production in the industrial producer fungus Ashbya gossypii. However, the molecular basis for the unusual sensitivity to uracil displayed by...

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Bibliographic Details
Main Author: Silva, Rui (author)
Other Authors: Aguiar, Tatiana Q. (author), Oliveira, Carla (author), Domingues, Lucília (author)
Format: article
Language:eng
Published: 2019
Subjects:
Online Access:http://hdl.handle.net/1822/58890
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/58890