Retarded PDI diffusion and a reductive shift in poise of the calcium depleted endoplasmic reticulum

Background: Endoplasmic reticulum (ER) lumenal protein thiol redox balance resists dramatic variation in unfolded protein load imposed by diverse physiological challenges including compromise in the key upstream oxidases. Lumenal calcium depletion, incurred during normal cell signaling, stands out a...

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Bibliographic Details
Main Author: Avezov, Edward (author)
Other Authors: Konno, Tasuku (author), Zyryanova, Alisa (author), Chen, Weiyue (author), Laine, Romain (author), Crespillo-Casado, Ana (author), Melo, Eduardo (author), Ushioda, Ryo (author), Nagata, Kazuhiro (author), Kaminski, Clemens F. (author), Harding, Heather P. (author), Ron, David (author)
Format: article
Language:eng
Published: 2018
Subjects:
Protein-disulfide-isomerase
Redox
Er
Erdj5
Inhibitor
Oxidation
Release
Sensor
Online Access:http://hdl.handle.net/10400.1/11358
Country:Portugal
Oai:oai:sapientia.ualg.pt:10400.1/11358

Internet

http://hdl.handle.net/10400.1/11358

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