Pd2Spermine Complex Shows Cancer Selectivity and Efficacy to Inhibit Growth of Triple-Negative Breast Tumors in Mice

Pd2Spm is a dinuclear palladium(II)-spermine chelate with promising anticancer properties against triple-negative breast cancer (TNBC), a breast carcinoma subset with poor prognosis and limited treatment options. The present study evaluated the in vitro and in vivo anticancer effects of Pd2Spm compa...

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Detalhes bibliográficos
Autor principal: Vojtek, Martin (author)
Outros Autores: Gonçalves-Monteiro, Salomé (author), Šeminská, Patrícia (author), Valová, Katarína (author), Bellón, Loreto (author), Dias-Pereira, Patrícia (author), Marques, Franklim (author), Marques, Maria P. M. (author), Carvalho, Ana L. M. Batista de (author), Mota-Filipe, Helder (author), Ferreira, Isabel M P L V O (author), Diniz, Carmen (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
Pd(II)-based drugs
cisplatin
metal complexes
triple-negative breast cancer
in vivo
xenografts
Texto completo:http://hdl.handle.net/10316/103192
País:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/103192

Texto Completo

http://hdl.handle.net/10316/103192

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