Cytoskeleton disruption by the metabolic inhibitor 3-bromopyruvate: implications in cancer therapy

The small molecule 3-bromopyruvate (3BP), is an anticancer molecule that acts by hindering glycolysis and mitochondrial function leading to energy depletion and consequently, to cell death. In this work we have focused on understanding how the glycolytic inhibition affects cancer cell structural fea...

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Detalhes bibliográficos
Autor principal: Azevedo-Silva, J. (author)
Outros Autores: Tavares-Valente, D. (author), Almeida, A. (author), Queiros, O. (author), Baltazar, Fátima (author), Ko, Y. H. (author), Pedersen, P. L. (author), Preto, Ana (author), Casal, Margarida (author)
Formato: article
Idioma:eng
Publicado em: 2022
Assuntos:
3-Bromopyruvate
Cytoskeleton
Cancer metabolism
Breast cancer
Ciências Naturais::Ciências Biológicas
Science & Technology
Texto completo:https://hdl.handle.net/1822/80184
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/80184

Texto Completo

https://hdl.handle.net/1822/80184

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