Enhanced performance of polymer-polymer aqueous two-phase systems using ionic liquids as adjuvants towards the purification of recombinant proteins

Protein biopharmaceuticals, among which interferon alpha-2b (IFNα-2b) that can be used in the treatment of chronic hepatitis C and hairy cell leukemia, have become an indispensable product of current medicine. However, their current high costs derived from the lack of cost-effective downstream strat...

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Bibliographic Details
Main Author: Castro, Leonor (author)
Other Authors: Pereira, Patrícia (author), Passarinha, Luís (author), Freire, Mara (author), Pedro, Augusto (author)
Format: article
Language:eng
Published: 2021
Subjects:
Adjuvants
Aqueous two-phase systems
Ionic liquids
Purification
Recombinant protein
Online Access:http://hdl.handle.net/10773/28739
Country:Portugal
Oai:oai:ria.ua.pt:10773/28739

Internet

http://hdl.handle.net/10773/28739

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