Chemical assessment and in vitro antioxidant capacity of Ficus carica latex

Ficus species possess latex-like material within their vasculatures, affording protection and selfhealing from physical attacks. In this work, metabolite profiling was performed on Ficus carica latex. Volatiles profile was determined by HS-SPME/GC-IT-MS, with 34 compounds being identified, distribut...

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Detalhes bibliográficos
Autor principal: Oliveira, A.P. (author)
Outros Autores: Silva, L.R. (author), Ferreres, F. (author), Pinho, P. Guedes de (author), Valentão, P. (author), Silva, Branca M. (author), Pereira, J.A. (author), Andrade, P.B. (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Texto completo:http://hdl.handle.net/10198/3116
País:Portugal
Oai:oai:bibliotecadigital.ipb.pt:10198/3116
Descrição
Resumo:Ficus species possess latex-like material within their vasculatures, affording protection and selfhealing from physical attacks. In this work, metabolite profiling was performed on Ficus carica latex. Volatiles profile was determined by HS-SPME/GC-IT-MS, with 34 compounds being identified, distributed by distinct chemical classes: 5 aldehydes, 7 alcohols, 1 ketone, 9 monoterpenes, 9 sesquiterpenes and 3 other compounds. Sesquiterpenes constituted the most abundant class in latex (ca. 91% of total identified compounds). Organic acids composition was also characterized, by HPLC-UV, and oxalic, citric, malic, quinic, shikimic and fumaric acids were determined. Malic and shikimic acids were present in higher amounts (ca. 26%, each). The antioxidant potential of this material was checked by distinct in vitro chemical assays. A concentration-dependent activity was noticed against DPPH, nitric oxide and superoxide radicals. Additionally, acetylcholinesterase inhibitory capacity was evaluated, but a weak effect was found.