Resistance to Recombinant Human Erythropoietin Therapy in a Rat Model of Chronic Kidney Disease Associated Anemia

This study aimed to elucidate the mechanisms explaining the persistence of anemia and resistance to recombinant human erythropoietin (rHuEPO) therapy in a rat model of chronic kidney disease (CKD)-associated anemia with formation of anti-rHuEPO antibodies. The remnant kidney rat model of CKD induced...

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Detalhes bibliográficos
Autor principal: Garrido, Patrícia (author)
Outros Autores: Ribeiro, Sandra (author), Fernandes, João (author), Vala, Helena (author), Rocha-Pereira, Petronila (author), Bronze-da-Rocha, Elsa (author), Belo, Luís (author), Costa, Elísio (author), Santos-Silva, Alice (author), Reis, Flávio (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
chronic kidney disease
anemia
remnant kidney rat model
resistance to rHuEPO therapy erythropoiesis
inflammation and fibrosis
kidney hypoxia
iron metabolism
Texto completo:http://hdl.handle.net/10400.19/3058
País:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/3058

Texto Completo

http://hdl.handle.net/10400.19/3058

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