Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice

Mitochondrial dysfunction is believed to participate in Huntington's disease (HD) pathogenesis. Here we compare the bioenergetic behavior of forebrain mitochondria isolated from different transgenic HD mice (R6/2, YAC128 and Hdh150 knock-in) and wild-type littermates with the first determinatio...

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Detalhes bibliográficos
Autor principal: Jorge M A Oliveira (author)
Outros Autores: Mika B Jekabsons (author), Sylvia Chen (author), Amy Lin (author), Cristina C Rego (author), Jorge Goncalves (author), Lisa M Ellerby (author), David G Nicholls (author)
Formato: article
Idioma:eng
Publicado em: 2007
Assuntos:
Texto completo:https://repositorio-aberto.up.pt/handle/10216/104704
País:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/104704