Mitochondrial dysfunction in Huntington's disease: the bioenergetics of isolated and in situ mitochondria from transgenic mice

Mitochondrial dysfunction is believed to participate in Huntington's disease (HD) pathogenesis. Here we compare the bioenergetic behavior of forebrain mitochondria isolated from different transgenic HD mice (R6/2, YAC128 and Hdh150 knock-in) and wild-type littermates with the first determinatio...

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Bibliographic Details
Main Author: Jorge M A Oliveira (author)
Other Authors: Mika B Jekabsons (author), Sylvia Chen (author), Amy Lin (author), Cristina C Rego (author), Jorge Goncalves (author), Lisa M Ellerby (author), David G Nicholls (author)
Format: article
Language:eng
Published: 2007
Subjects:
Medicina básica
Basic medicine
Online Access:https://repositorio-aberto.up.pt/handle/10216/104704
Country:Portugal
Oai:oai:repositorio-aberto.up.pt:10216/104704

Internet

https://repositorio-aberto.up.pt/handle/10216/104704

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