Phenolic acid derivatives with potential anticancer properties––a structure–activity relationship study. Part 1: Methyl, propyl and octyl esters of caffeic and gallic acids

The antiproliferative and cytotoxic properties of polyphenolic acid derivatives, structurally related with the natural models caffeic and gallic acids, have been tested in human cervix adenocarcinoma cells (HeLa). Simultaneous structural information was obtained for these compounds through theoretic...

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Bibliographic Details
Main Author: Fiuza, S. M. (author)
Other Authors: Gomes, C. (author), Teixeira, L. J. (author), Girão da Cruz, M. T. (author), Cordeiro, M. N. D. S. (author), Milhazes, N. (author), Borges, F. (author), Marques, M. P. M. (author)
Format: article
Language:eng
Published: 2004
Subjects:
Antineoplastic Agents
Caffeic Acids
Cell Line
Cell Survival
Drug Screening Assays, Antitumor
Esters
Gallic Acid
Humans
Hydroxybenzoates
Inhibitory Concentration 50
Methylation
Molecular Structure
Structure-Activity Relationship
Online Access:http://hdl.handle.net/10316/45150
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/45150

Internet

http://hdl.handle.net/10316/45150

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