Dendrimer-based Report-Eradication Antineoplasic Machines

Polyurea (PURE) dendrimers are a versatile platform for cancer nanotheranostics. The aim of this study was to improve the therapeutic efficacy of carboplatin by a buthionine sulfoximine (BSO) triggered inhibition of glutathione synthesis. BSO nanodelivery was achieved by controlled release from an e...

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Detalhes bibliográficos
Autor principal: Mota, Pedro Manuel Barbosa (author)
Formato: masterThesis
Idioma:eng
Publicado em: 2019
Assuntos:
Ovarian cancer
Buthionine sulfoximine
Chemoresistance
Glutathione
Polyurea dendrimers
Controlled drug delivery
Domínio/Área Científica::Engenharia e Tecnologia::Engenharia Química
Texto completo:http://hdl.handle.net/10362/38193
País:Portugal
Oai:oai:run.unl.pt:10362/38193

Texto Completo

http://hdl.handle.net/10362/38193

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