Aza vinyl sulfones: Synthesis and evaluation as antiplasmodial agents

A series of novel aza vinyl sulfones were designed, synthesized in good yields and evaluated as antiplasmodial agents. Tested compounds did not show activity against papain or the Plasmodium falciparum cysteine protease falcipain-2. However, a number of the new compounds effectively inhibited the in...

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Detalhes bibliográficos
Autor principal: Glória, Paulo M. C. (author)
Outros Autores: Gut, Jiri (author), Gonçalves, Lídia M. (author), Rosenthal, Philip J. (author), Moreira, Rui (author), Santos, Maria M. M. (author)
Formato: article
Idioma:eng
Publicado em: 2013
Assuntos:
Texto completo:http://hdl.handle.net/10451/8155
País:Portugal
Oai:oai:repositorio.ul.pt:10451/8155