Organotypic 3D decellularized matrix tumor spheroids for high-throughput drug screening

Decellularized extracellular matrix (dECM) is emerging as a valuable tool for generating 3D in vitro tumor models that better recapitulate tumor-stroma interactions. However, the development of dECM-3D heterotypic microtumors exhibiting a controlled morphology is yet to be materialized. Precisely co...

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Bibliographic Details
Main Author: Ferreira, Luís P. (author)
Other Authors: Gaspar, Vítor M. (author), Mendes, Luís (author), Duarte, Iola F. (author), Mano, João F. (author)
Format: article
Language:eng
Published: 2022
Subjects:
Online Access:http://hdl.handle.net/10773/34743
Country:Portugal
Oai:oai:ria.ua.pt:10773/34743