Suppression therapy as novel approach for genetic diseases and cancer

Premature translation-termination codons (PTCs or nonsense codons) can arise from mutations in germ or somatic cells. The introduction of a PTC into an mRNA can trigger nonsense-mediated decay (NMD), an important mRNA surveillance mechanism that typically recognizes and degrades mRNAs containing PTC...

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Bibliographic Details
Main Author: Gomes-Duarte, Andreia (author)
Other Authors: Dias, Parícia (author), Romão, Luísa (author)
Format: conferenceObject
Language:eng
Published: 2017
Subjects:
Suppression Therapy
Genetic Diseases
Cancer
Premature Translation-termination Codons
Genómica Funcional e Estrutural
Expressão Génica
Online Access:http://hdl.handle.net/10400.18/5153
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/5153

Internet

http://hdl.handle.net/10400.18/5153

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