Quercetin enhances 5-fluorouracil-induced apoptosis in MSI colorectal cancer cells through p53 modulation

Colorectal tumors (CRC) with microsatellite instability (MSI) show resistance to chemotherapy with 5-fluorouracil (5-FU), the most widely used pharmacological drug for CRC treatment. The aims of this study were to test the ability of quercetin (Q) and luteolin (L) to increase sensitivity of MSI CRC...

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Bibliographic Details
Main Author: Xavier, Cristina P. R. (author)
Other Authors: Lima, Cristóvão F. (author), Wilson, Cristina Pereira (author)
Format: conferenceObject
Language:eng
Published: 2011
Online Access:https://hdl.handle.net/1822/16015
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/16015