Synthesis of beta-benzo[b]thienyldehydrophenylalanine derivatives by one pot palladium-catalyzed borylation and Suzuki coupling (BSC) and metal-assisted intramolecular cyclization: studies of fluorescence and antimicrobial activity

Palladium-catalyzed borylation and Suzuki coupling (BSC) in a one pot procedure was successfully applied to the synthesis of several beta-substituted dehydrophenylalanines in the benzo[b]thiophene series maintaining the stereochemistry of the starting materials. Bromobenzo[b]thiophenes bearing an or...

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Bibliographic Details
Main Author: Abreu, Ana S. (author)
Other Authors: Ferreira, Paula M. T. (author), Queiroz, Maria João R. P. (author), Ferreira, Isabel C. F. R. (author), Calhelha, Ricardo C. (author), Estevinho, Letícia M. (author)
Format: article
Language:eng
Published: 2005
Subjects:
Dehydrophenylalanines
Benzothiophenes
Borylation
Suzuki coupling
Cyclization
Indoles
Fluorescence
Antimicrobial activity
Science & Technology
Online Access:http://hdl.handle.net/1822/3045
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/3045

Internet

http://hdl.handle.net/1822/3045

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