Production of orotic acid by a Klura3 mutant of Kluyveromyces lactis

We demonstrated that a Klura3, mutant of the yeast Kluyveromyces lactis is able to produce and secrete into the growth medium considerable amounts of orotic acid. Using yeast extractpeptoneglucose (YPD) based media we optimized production conditions in flask and bioreactor cultures. With cells grown...

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Detalhes bibliográficos
Autor principal: Carvalho, Nuno (author)
Outros Autores: Coelho, Eduardo João Louro (author), Gales, Luís (author), Costa, Vítor (author), Teixeira, J. A. (author), Ferreira, Pedro Moradas (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
Bioprocess optimization
Kluyveromyces lactis
KlURA3
Orotic acid
Yeast biotechnology
Science & Technology
Texto completo:http://hdl.handle.net/1822/41794
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/41794

Texto Completo

http://hdl.handle.net/1822/41794

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