Production of orotic acid by a Klura3 mutant of Kluyveromyces lactis

We demonstrated that a Klura3, mutant of the yeast Kluyveromyces lactis is able to produce and secrete into the growth medium considerable amounts of orotic acid. Using yeast extractpeptoneglucose (YPD) based media we optimized production conditions in flask and bioreactor cultures. With cells grown...

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Bibliographic Details
Main Author: Carvalho, Nuno (author)
Other Authors: Coelho, Eduardo João Louro (author), Gales, Luís (author), Costa, Vítor (author), Teixeira, J. A. (author), Ferreira, Pedro Moradas (author)
Format: article
Language:eng
Published: 2016
Subjects:
Bioprocess optimization
Kluyveromyces lactis
KlURA3
Orotic acid
Yeast biotechnology
Science & Technology
Online Access:http://hdl.handle.net/1822/41794
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/41794

Internet

http://hdl.handle.net/1822/41794

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