Signaling Pathways Driving Aberrant Splicing in Cancer Cells

Aberrant profiles of pre-mRNA splicing are frequently observed in cancer. At the molecular level, an altered profile results from a complex interplay between chromatin modifications, the transcriptional elongation rate of RNA polymerase, and effective binding of the spliceosome to the generated tran...

Full description

Bibliographic Details
Main Author: Gonçalves, Vânia (author)
Other Authors: Pereira, Joana F.S. (author), Jordan, Peter (author)
Format: article
Language:eng
Published: 2018
Subjects:
Alternative Splicing
Cancer Cell
Genetic Program
Signaling Pathway
Tumor Microenvironment
Tumorigenesis
Vias de Transdução de Sinal e Patologias Associadas
Online Access:http://hdl.handle.net/10400.18/5461
Country:Portugal
Oai:oai:repositorio.insa.pt:10400.18/5461

Internet

http://hdl.handle.net/10400.18/5461

Similar Items