Signaling Pathways Driving Aberrant Splicing in Cancer Cells

Aberrant profiles of pre-mRNA splicing are frequently observed in cancer. At the molecular level, an altered profile results from a complex interplay between chromatin modifications, the transcriptional elongation rate of RNA polymerase, and effective binding of the spliceosome to the generated tran...

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Detalhes bibliográficos
Autor principal: Gonçalves, Vânia (author)
Outros Autores: Pereira, Joana F.S. (author), Jordan, Peter (author)
Formato: article
Idioma:eng
Publicado em: 2018
Assuntos:
Alternative Splicing
Cancer Cell
Genetic Program
Signaling Pathway
Tumor Microenvironment
Tumorigenesis
Vias de Transdução de Sinal e Patologias Associadas
Texto completo:http://hdl.handle.net/10400.18/5461
País:Portugal
Oai:oai:repositorio.insa.pt:10400.18/5461

Texto Completo

http://hdl.handle.net/10400.18/5461

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