How mRNA translation can modulate nonsense-mediated decay
About one third of the gene mutations found in human genetic disorders, including cancer, result in premature translation-termination codons (PTCs) and the rapid degradation of the corresponding mRNAs by nonsense-mediated decay (NMD). However, we have found that human mRNAs with a PTC in close proxi...
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| Format: | lecture |
| Language: | eng |
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2017
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| Online Access: | http://hdl.handle.net/10400.18/5423 |
| Country: | Portugal |
| Oai: | oai:repositorio.insa.pt:10400.18/5423 |