Heterocyclic synthesis with nitriles: synthesis of pyrazolopyrimidine and pyrazolopyridine derivatives

The reaction of N1-substituted-5-amino-4-cyanopyrazoles with malononitrile and diethylmalonate occurs with formation of 6-substituted pyrazolo[3,4-d]pyrimidines, and pyrazolo[3,4-b]pyridines respectively. The structures of the products and conceivable mechanisms are discussed.

Detalhes bibliográficos
Autor principal: Salaheldin, Abdellatif M. (author)
Outros Autores: Campos, Ana M. F. Oliveira (author), Rodrigues, Lígia M. (author)
Formato: article
Idioma:eng
Publicado em: 2009
Assuntos:
Texto completo:http://hdl.handle.net/1822/12593
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/12593