Sirolimus ameliorates cyclosporin-induced nephrotoxicity in a rat model – focus on renal lesions, oxidative stress, inflammation, proliferation and angiogenesis

Sirolimus (SRL) have been pointed as a feasible option for minimize the use of cyclosporine A (CsA), especially because os putatively less nephrotoxicity. However, the cellular mechanism underlying the renoprotection remains to be elucidated, and the clinical data is yet insufficient. This stuty aim...

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Bibliographic Details
Main Author: Sereno, José (author)
Other Authors: Romão, Ana M. (author), Teixeira, Margarida (author), Parada, Belmiro (author), Santos, Paulo R. (author), Alves, Rui (author), Mega, Cristina (author), Vala, Helena (author), Lemos, Edite T. (author), Teixeira, Frederico (author), Reis, Flávio (author)
Format: conferenceObject
Language:eng
Published: 2015
Subjects:
nephropathy
Sirolimus (SRL)
cyclosporine A (CsA)
nephrotoxicity
Online Access:http://hdl.handle.net/10400.19/2729
Country:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/2729

Internet

http://hdl.handle.net/10400.19/2729

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