Generating a personalized immunotherapy by reprogramming fibroblasts to regulatory T cells
For a long time, cell development was thought to be a unidirectional process. Cellular identity is acquired and maintained through the expression of lineage specific transcription factors (TFs). Several studies starting in mid 19s that culminated in the complete reversion of a somatic cell to a plur...
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Format: | masterThesis |
Language: | por |
Published: |
2017
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Online Access: | http://hdl.handle.net/1822/77411 |
Country: | Portugal |
Oai: | oai:repositorium.sdum.uminho.pt:1822/77411 |