Generating a personalized immunotherapy by reprogramming fibroblasts to regulatory T cells

For a long time, cell development was thought to be a unidirectional process. Cellular identity is acquired and maintained through the expression of lineage specific transcription factors (TFs). Several studies starting in mid 19s that culminated in the complete reversion of a somatic cell to a plur...

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Bibliographic Details
Main Author: Ferreira, Alexandra Gabriela Barros (author)
Format: masterThesis
Language:por
Published: 2017
Subjects:
Online Access:http://hdl.handle.net/1822/77411
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/77411