Critical perspective on the consequences of the limited availability of kinetic data in metabolic dynamic modeling

Detailed kinetic models at the network reaction level are usually constructed using enzymatic mechanistic rate equations and the associated kinetic parameters. However, during the cellular life cycle thousands of different reactions occur, which makes it very difficult to build a detailed large-scal...

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Detalhes bibliográficos
Autor principal: Costa, Rafael S. (author)
Outros Autores: Machado, C. D. (author), Rocha, I. (author), Ferreira, Eugénio C. (author)
Formato: article
Idioma:eng
Publicado em: 2011
Assuntos:
Texto completo:https://hdl.handle.net/1822/16719
País:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/16719