tRNA-modifying enzyme mutations induce codon-specific mistranslation and protein aggregation in yeast

Protein synthesis rate and accuracy are tightly controlled by the cell and are essential for proteome homoeostasis (proteostasis); however, the full picture of how mRNA translational factors maintain protein synthesis accuracy and co-translational protein folding are far from being fully understood....

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Detalhes bibliográficos
Autor principal: Tavares, Joana F. (author)
Outros Autores: Davis, Nick K. (author), Poim, Ana (author), Reis, Andreia (author), Kellner, Stefanie (author), Sousa, Inês (author), Soares, Ana R. (author), Moura, Gabriela M. R. (author), Dedon, Peter C. (author), Santos, Manuel (author)
Formato: article
Idioma:eng
Publicado em: 2021
Assuntos:
(5-10) tRNA modifying enzymes
Protein aggregation
Yeast
tRNA
Proteome
Texto completo:http://hdl.handle.net/10773/30815
País:Portugal
Oai:oai:ria.ua.pt:10773/30815

Texto Completo

http://hdl.handle.net/10773/30815

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