Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat

Our aim was to study the effect of a broad range of recombinant human erythropoietin (rHuEPO) doses on hematological and biochemical parameters, blood pressure (BP), renal function and damage in the rat, focusing on endothelial nitric oxide synthase (eNOS) and hypoxia-inducible factors (HIFs). Male...

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Detalhes bibliográficos
Autor principal: Ribeiro, Sandra (author)
Outros Autores: Garrido, Patrícia (author), Fernandes, João (author), Vala, Helena (author), Rocha-Pereira, Petronila (author), Costa, Elísio (author), Belo, Luís (author), Reis, Flávio (author), Santos-Silva, Alice (author)
Formato: article
Idioma:eng
Publicado em: 2016
Assuntos:
reticulocytes
recombinant human erythropoietin therapy
hypoxia
direct renal vascular effects
endothelial nitric oxide synthase
hypertension
Texto completo:http://hdl.handle.net/10400.19/3167
País:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/3167

Texto Completo

http://hdl.handle.net/10400.19/3167

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