Impaired renal endothelial nitric oxide synthase and reticulocyte production as modulators of hypertension induced by rHuEPO in the rat

Our aim was to study the effect of a broad range of recombinant human erythropoietin (rHuEPO) doses on hematological and biochemical parameters, blood pressure (BP), renal function and damage in the rat, focusing on endothelial nitric oxide synthase (eNOS) and hypoxia-inducible factors (HIFs). Male...

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Bibliographic Details
Main Author: Ribeiro, Sandra (author)
Other Authors: Garrido, Patrícia (author), Fernandes, João (author), Vala, Helena (author), Rocha-Pereira, Petronila (author), Costa, Elísio (author), Belo, Luís (author), Reis, Flávio (author), Santos-Silva, Alice (author)
Format: article
Language:eng
Published: 2016
Subjects:
reticulocytes
recombinant human erythropoietin therapy
hypoxia
direct renal vascular effects
endothelial nitric oxide synthase
hypertension
Online Access:http://hdl.handle.net/10400.19/3167
Country:Portugal
Oai:oai:repositorio.ipv.pt:10400.19/3167

Internet

http://hdl.handle.net/10400.19/3167

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