In vitro and in vivo studies of temozolomide loading in zeolite structures as drug delivery systems for glioblastoma

Zeolites Y (faujasite) and MOR (mordonite) were used as hosts for temozolomide (TMZ), a current good-standard chemotherapeutic agent used in the treatment of glioblastoma brain tumors. TMZ was loaded into zeolites by liquid-phase adsorption at controlled pH. FTIR, 1H NMR, MS, SEM, UV/vis and chemica...

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Bibliographic Details
Main Author: Martinho, Olga (author)
Other Authors: Vilaça, Natália (author), Castro, Paulo J. G. (author), Amorim, Ricardo (author), Fonseca, António M. (author), Baltazar, Fátima (author), Reis, R. M. (author), Neves, Isabel C. (author)
Format: article
Language:eng
Published: 2015
Subjects:
Science & Technology
Online Access:http://hdl.handle.net/1822/40263
Country:Portugal
Oai:oai:repositorium.sdum.uminho.pt:1822/40263

Internet

http://hdl.handle.net/1822/40263

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