Human serum albumin enhances DNA transfection by lipoplexes and confers resistance to inhibition by serum

Cationic liposome-DNA complexes ([`]lipoplexes') are used as gene delivery vehicles and may overcome some of the limitations of viral vectors for gene therapy applications. The interaction of highly positively charged lipoplexes with biological macromolecules in blood and tissues is one of the...

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Bibliographic Details
Main Author: Simões, Sérgio (author)
Other Authors: Slepushkin, Vladimir (author), Pires, Pedro (author), Gaspar, Rogério (author), Pedroso de Lima, Maria C. (author), Düzgünes, Nejat (author)
Format: article
Language:eng
Published: 2000
Subjects:
Gene therapy
Cationic liposome
Human serum albumin
Macrophage
In vivo
Gene delivery
Online Access:http://hdl.handle.net/10316/5812
Country:Portugal
Oai:oai:estudogeral.sib.uc.pt:10316/5812

Internet

http://hdl.handle.net/10316/5812

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