Nucleic acid changes during photodynamic inactivation of bacteria by cationic porphyrins

Light activation of photosensitizing dyes in presence of molecular oxygen generates highly cytotoxic reactive oxygen species leading to cell inactivation. Nucleic acids are molecular targets of this photodynamic action but not considered the main cause of cell death. The in vivo effect of the photod...

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Bibliographic Details
Main Author: Alves, Eliana (author)
Other Authors: Faustino, Maria A. F. (author), Tomé, João P. C. (author), Neves, Maria G. P. M. S. (author), Tomé, Augusto C. (author), Cavaleiro, José A. S. (author), Cunha, Ângela (author), Gomes, Newton C. M. (author), Almeida, Adelaide (author)
Format: article
Language:eng
Published: 2019
Subjects:
Cationic porphyrins
Escherichia coli
Genomic DNA
Photodynamic inactivation
RNA
Reactive oxygen species
Staphylococcus warneri
Online Access:http://hdl.handle.net/10773/25620
Country:Portugal
Oai:oai:ria.ua.pt:10773/25620

Internet

http://hdl.handle.net/10773/25620

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