N-Cinnamoylated Chloroquine Analogues as Dual-Stage Antimalarial Leads

The control of malaria is challenged by drug resistance, and new antimalarial drugs are needed. New drug discovery efforts include consideration of hybrid compounds as potential multitarget antimalarials. Previous work from our group has demonstrated that hybrid structures resulting from cinnamic ac...

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Bibliographic Details
Main Author: Perez, Bianca C. (author)
Other Authors: Teixeira, Catia (author), Albuquerque, Ines S. (author), Gut, Jiri (author), Rosenthal, Philip J. (author), Gomes, Jose R. B. (author), Prudencio, Miguel (author), Gomes, Paula (author)
Format: article
Language:eng
Published: 1000
Subjects:
LIVER-STAGE
PLASMODIUM-FALCIPARUM
INHIBITORY-ACTIVITY
MALARIA
DERIVATIVES
HEMATIN
PRIMAQUINE
MOLECULES
PARASITE
Online Access:http://hdl.handle.net/10773/19218
Country:Portugal
Oai:oai:ria.ua.pt:10773/19218

Internet

http://hdl.handle.net/10773/19218

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